Reproductive Cancer Group
Understanding the cross-talk between ovarian cancer cells and the tumour micro-environment may allow us to understand how ovarian cancer spreads, its resistance to chemotherapy, and how to identify novel biomarkers for ovarian cancer detection.
Our current studies focus on the interactions of peritoneal cancer and ovarian cancer, and the mechanisms of how extracellular matrix proteins and proteases promote motility and tumour spread in ovarian cancer.
The Reproductive Cancer Group builds on an exciting and unique discovery by Dr Ricciardelli—that an extracellular matrix protein called versican correlates with cancer spread in prostate and breast cancer. This discovery suggests that cancer cells utilise proteins from the surrounding stromal cells to aid their movement and has led to versican protein expression being examined in many different cancer types.
Dr Carmela Ricciardelli
Dr Carmela Ricciardelli is a cancer cell biologist in the Discipline of Obstetrics and Gynaecology at the University of Adelaide. She was awarded a Tall Poppy Award in 2005 for outstanding achievement in the field of biomedical and clinical science. In 2007 she was the recipient of the highly competitive Hilda Farmer Fellowship in the Faculty of Health and Medical Sciences, which has enabled her to build a reproductive cancer research group in the Discipline of Obstetrics and Gynecology, the University of Adelaide.
- Professor Ray Rodgers - Robinson Research Institute
- Associate Professor Darryl Russell - Robinson Research Institute
- Professor Peter Hoffman - University of South Australia
- Dr Andrew Stephens - Hudson Institute of Medical Research, Victoria
- Professor Rik Thompson - Institute of Health and Biomedical Innovation, Queensland
Related areas of research
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