Intestinal Nutrient Sensing Group

The Intestinal Nutrient Sensing Group undertakes research focused on the nature of the intestinal sweet taste system.

This system detects intestinal sweet stimuli and, in turn, can regulate the release of gut hormones and control of glucose absorption. We have revealed specific regulation of this system in health, and dysregulation in diabetes, critical illness and obesity. We have access to genetic and disease models and a wide range of human tissue to answer our research questions, including:

  • Do artificial sweeteners influence intestinal sweet sensing and glucose absorption in humans?
  • Does blocking intestinal sweet taste receptors reduce glucose uptake in patients with type 2 diabetes?

The Intestinal Nutrient Sensing Group collaborates with researchers from basic and clinical science backgrounds and industry, strengthening our ability to deliver novel therapies for obesity and type 2 diabetes.

For our latest clinical trials, please refer to Sweet taste diabetes research trial on the Faculty of Health and Medical Sciences’ Participate in research webpage.

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  • Lead researcher

    Associate Professor Richard L Young

    Associate Professor Richard L Young is a Senior Research Fellow in the Adelaide Medical School at the University of Adelaide, and a Senior Research Fellow and faculty member at the South Australian Health and Medical Research Institute (SAHMRI) in Nutrition and Metabolism. He is a member of the NHMRC Centre of Research Excellence in Translating Nutritional Science to Good Health - an exceptional framework for translational researchers in endocrinology and gastroenterology.

  • Research team

    Research team Role
    Associate Professor Richard L Young Lead researcher
    Denise Kreuch PhD candidate
    Braden Rose PhD candidate
    Nicole J Isaacs Research officer
    Nektaria Pezos Research officer
  • Partnerships

    Partner Institution/Organisation
    Professor Chris Rayner University of Adelaide
    Dr Tongzhi Wu University of Adelaide
    Dr Nam Nguyen University of Adelaide
    Professor Michael Horowitz University of Adelaide
    Professor Geraint Rogers SAHMRI Infection and Immunity
    Professor Damien Keating Flinders University
    Charles-Henri Malbert INRA Saint-Gilles, France
    Dr Kerry Ivey Harvard University, Cambridge MA, USA
  • Related areas of research

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