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Intestinal Nutrient Sensing Group

The Intestinal Nutrient Sensing Group undertakes research focused on the form and function of the intestinal sweet taste system.

The intestinal sweet taste system senses intestinal glucose and regulates the release of gut hormones and control of glucose absorption. Our research has revealed regulation of this system by luminal and blood glucose, and dysregulation in human diabetes, critical illness and obesity. We have access to genetic and disease models and a wide range of human tissue to answer our research questions, including:

  • Do artificial sweeteners influence intestinal sweet sensing and glucose absorption in humans?
  • Does blocking intestinal sweet taste receptors reduce glucose uptake in patients with type 2 diabetes?

The Intestinal Nutrient Sensing Group has major collaborators from basic and clinical science backgrounds and industry, strengthening our ability to deliver novel therapies for obesity and type 2 diabetes.

Lead researcher: Associate Professor Richard L Young

Research team

Research support


  • Damien Keating - Flinders University
  • Nam Nguyen - University of Adelaide
  • Christopher Rayner - University of Adelaide
  • Margaret Jackson - Pfizer International, Boston, USA

Interested in undertaking a postgraduate research degree with us?

We offer exciting opportunities for researchers at the honours, masters and PhD levels. Our research degrees are open to students from a broad range of backgrounds, and range from basic sciences to clinical research. If you are interested in human health, consider furthering your research career with us.