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Cancer Treatment Toxicities Group

Gastrointestinal symptoms that arise as a consequence of systemic cancer treatment continue to be some of the most common and costly adverse effects of cancer therapy.  

Our research looks at the pressing clinical importance of better management of cancer treatment-related toxicity, particularly toxicity effects on the gastrointestinal tract. Acute gastrointestinal symptoms remain a significant challenge to delivering optimally effective cancer treatment with minimal impact on quality of life—which is the ultimate goal of excellent cancer care. 

The Cancer Treatment Toxicities Group investigates chemotherapy, radiotherapy and targeted therapy-induced whole gut damage, and the efficacy of new agents in prevention and treatment. We are also interested in how toxicity of the cancer treatment links to other treatment symptoms, such has pain and cognitive decline.

In addition, our group has ongoing patient studies looking to determine the risk factors associated with poor cancer treatment outcomes and how to better predict side effects. 

The Cancer Treatment Toxicities Group is comprised of four collaborative research laboratories: the Gastrointestinal Pathophysiology Laboratory led by Associate Professor Joanne Bowen, the Gut Microbiome Laboratory led by Professor Rachel Gibson, the Clinical Pharmacogenomics Laboratory led by Dr Janet Coller, and the Mucositis Laboratory led by Professor Dorothy Keefe.

Lead researcher: Associate Professor Joanne Bowen

Research team

Research support
  • Imogen Ball
  • Samantha Korver
  • Kate Secombe
  • Joseph Shirren
  • Romany Stansborough
  • Ysabella Van Sebille
  • Anthony Wignall


Interested in undertaking a postgraduate research degree with us?

We offer exciting opportunities for researchers at the honours, masters and PhD levels. Our research degrees are open to students from a broad range of backgrounds, and range from basic sciences to clinical research. If you are interested in human health, consider furthering your research career with us.