DRMCRL Visiting Professor Iggo publishes on breast cancer organoid and intraductal models

Professor Richard Iggo, Professor of Cell Biology, University of Bordeaux / Visiting Professor, University of Adelaide has published the methodology, currently utilised at the DRMCRL, for creating breast cancer models by transducing tumor cells and normal mammary epithelial cells with lentiviral vectors in organoid culture and injecting them into the mammary ducts of mice. This article entitled "Modeling breast cancer in organoid and intraductal models" was published in Mammary Stem Cells, a Methods in Molecular Biology book series, and describes the protocols to create estrogen receptor positive (ER+) and androgen receptor positive (AR+) breast cancer models by combining organoid culture with mammary intraductal injection.  doi: 10.1007/978-1-0716-2193-6_13