AmpuEase – Transtibial Amputee Study
A poorly fitting prosthetic socket can greatly affect the daily lives of amputees – leading to 25% to 50% of amputees eventually abandoning their prosthesis.

The AmpuEase research team is on a mission to solve the everyday challenges transtibial amputees face with their prosthetic sockets. By combining detailed surveys, group discussions, and cutting-edge medical imaging, the team will uncover the root causes of discomfort and fit issues. Participants’ insights and scans will drive the design of an adjustable, custom-fit socket, with prototypes tested by real users to ensure optimal comfort and function.
Who can participate?
Below-knee amputees seeking to improve comfort and mobility, for themselves and others, are invited to get involved.
Eligibility Criteria:
- At least 18 years of age
- Underwent transtibial amputation at least 18-months prior
- Have a stable residual limb condition without active infections or significant oedema
- Have ever used a prosthetic limb for daily activities
- Are in good general health as determined by a medical professional
- Do not suffer from claustrophobia or other medical conditions incompatible with medical imaging
- Are willing and able to attend all study sessions
- Are able to give written informed consent
- Can understand written and verbal English.
What am I being invited to do?
- Read the Participant Information Sheet
- Undertake the Online survey and consent
- Vital signs taken and external scan, MRI and CT scans of your residual limb at Jones radiology, SAHMRI CRIC.
- Group discussion session (~4 participants per session, approx. 2 hrs) and socket evaluation survey.
- Reflection diary – uploading photos/video of significant issues with prosthetic socket over 5 days.
An Honorarium of $150 will be presented to participants at the end of the study. Reimbursement will be available for some distance travelled and parking.
This study is supported by a Lifetime Support Authority Project Grant (R24020).
Ethics has been approved by Central Adelaide Local Health Network Human Research Ethics Committee (CALHN HREC) (H-2025-21383) and The University of Adelaide HREC.
Contact
For further information, or if you would like to participate in this research, please contact Dr Ryan Quarrington.