Martelotto Lab: Single Cell & Spatial Omics

Our research

The Single Cell and Spatial-Omics Lab at ACE/SAIGENCI is a state-of-the-art incubator for the development and evaluation of new single cell, spatial and genomics tools and methodologies. As an innovation team, we aim to provide a creative hub for generating new technologies, equipment evaluation, protocol development and informatics tool integration. Our lab is dedicated to constantly evolving to keep up with the fast-paced advancements of the genomics field, but our focus remains on developing technologies that have the potential to advance research and its practical application for the wider scientific community.

Our team is highly collaborative and technology-driven, providing comprehensive technical and intellectual support to researchers at all stages of experimentation, including planning, design, execution, and interpretation. We offer a one-stop-shop for collaborators looking to access novel technology, receive technical and developmental support, and troubleshoot any issues that arise.

We are particularly interested in the development of single cell and spatial-omics technologies, which enable researchers to analyse individual cells or spatially resolve the gene expression of different cells within a tissue sample. By using these cutting-edge techniques, we aim to unravel the complexity of biological systems and contribute to the development of new therapeutic strategies.

As part of our commitment to advancing the field, we actively seek collaborations with researchers from different backgrounds and disciplines, including academia, industry, and government. By working together, we believe we can accelerate the development and application of new technologies that have the potential to transform scientific research and improve human health.

Student projects

In the pursuit of scientific excellence, the central mission of our laboratory is to establish a pioneering Single Cell and Spatial-Omics Laboratory, specifically tailored to the research and development of advanced methods in the fields of cancer and epigenetics. With over 30 ongoing national and international collaborations, we strive to seamlessly integrate single cell and spatial technologies, whilst continuously improving, developing, and implementing state-of-the-art methodologies. Our ambitious vision is underpinned by the goal of enhancing our understanding of the intricate interplay at the most fundamental level of cancer, ultimately driving discoveries with profound clinical impact.

Our laboratory aims to serve as a premier cancer research enabling platform, providing access to cutting-edge infrastructure, equipment, and expertise to both basic and clinical researchers. This commitment to excellence facilitates high-impact publications, successful grant applications, and fruitful collaborations on the national and international stage. A crucial component of our success lies in the assemblage of a highly skilled and dynamic team, composed of individuals who are adept at navigating the ever-evolving landscape of science and technology, and who are capable of expertly managing and coordinating projects of all magnitudes.

The Single Cell and Spatial-Omics Lab has been meticulously designed to offer unparalleled access to groundbreaking spatial and single cell technologies for academia and industry alike. Our colocalisation of spatial technologies with a comprehensive range of supportive equipment enables us to provide a full spectrum of specialised services, empowering researchers to concentrate on scientific discovery. As an innovative and collaborative incubator, we pride ourselves on our capacity to develop and evaluate novel single cell, spatial, and genomics tools and methodologies, while providing an intellectual hub for technology generation, equipment evaluation, and protocol development. Our unwavering dedication to the genomics field ensures that we remain at the forefront of scientific advancement, always seeking to develop technologies that propel both research and practical applications forward.

We actively encourage and foster collaborations with researchers from diverse backgrounds and disciplines, including academia, industry, and government. It is through these synergistic partnerships that we believe we can expedite the development and application of transformative technologies, revolutionising scientific research and improving human health.

In our pursuit of the brightest minds, we continuously seek individuals who are diligent, agile, and experienced, possessing a strong understanding of current technologies and the state of scientific research. Our team members are expected to act as extensions of collaborating labs and research groups, providing expert consultation and ensuring the success of every project. By assembling a team of such talented individuals, we aim to cement our position as a world-class research enabling hub, driving advancements in the field and contributing to the global research community.