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School of Medical Sciences
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The University of Adelaide
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Featured Early Career Researchers

Dr Mark Hutchinson, NHMRC CJ Martin Post Doctoral Research Fellow

Dr Mark Hutchinson completed a BSc majoring in Pharmacology, Microbiology & Immunology at the University of Adelaide (1998). He continued his studies in Pharmacology with  honours (1999) & PhD (2004) examining opioid metabolism & opioid immunodulation, respectively. In 2004 he was awarded the FreshScience prize for communication of science in the media.  He moved to Boulder, Colorado in 2005 to undertake Postdoctoral training in the world leading research group of Prof Linda Watkins in the Center for Neuroscience at the University of Colorado at Boulder. Here he pioneered with Prof Watkins the research which has lead to the discovery of novel drugs activity at innate immune receptors. Moreover, his research has lead to the implication of the brain immune cells in the action of drugs of dependence and the negative side effects of pain killers. Dr Hutchinson was awarded an NHMRC CJ Martin Fellowship in 2007. He returned to Adelaide in 2009 to continue his research in the Discipline of Pharmacology, University of Adelaide. He has numerous peer reviewed publications, review papers and book chapters, several patents and is frequently asked to speak at national and international conferences and symposia. He was recently awarded the Denis Wade Early Career Researcher Award (2009) and is a SA Tall Poppy Finalist (2010).

 
 

Dr Tania Crotti, NHMRC CJ Martin Post Doctoral Research Fellow

Dr Tania Crotti was awarded a BHealthSci (Hons) from The University of Adelaide in 1997 then worked as a Research assistant in the Discipline of Pathology, University of Adelaide.  Tania completed her PhD on “The mechanisms responsible for pathological bone remodelling in inflammatory conditions” in 2002 (funded by a Dora Lush, NHMRC Scholarship).  The publications arising from this work contributed to defining the cellular source and role of the RANKL/OPG system in pathological bone resorption in inflammatory arthritis and peri-implant osteolysis associated with failed orthopaedic implants.
Dr Crotti subsequently worked as a postdoctoral fellow at the Harvard Affiliated Beth Israel Deaconess Medical Center, Boston USA.  She was awarded a NHMRC CJ Martin Fellowship to characterize the mechanisms regulating expression of the beta 3 integrin gene during osteoclast differentiation.   In 2006 Dr Crotti was awarded an American Arthritis Foundation Fellowship to investigate the role of cell-substrate interactions in regulating molecular pathways and genes associated with terminal osteoclast activation.  Her postdoctoral work has been recognized in her receipt of several research awards including a Novartis Young Investigator Award at the Joint Meeting of the ECT/IBMs in Geneva, Switzerland (2005); the ASBMR Harold M. Frost Young Investigator Award at the International Sun Valley Workshop on Skeletal Biology (2005), and most recently a John Haddad Young Investigator Award from AIMMS and ASBMR (2008) Colorado, USA.
Dr Crotti returned to Adelaide during 2008 to continue her work in the emerging field of esteoimmunology. Her main research focus is to unravel the mediators of osteoclast differentiation and activation in order to arrest the localized bone loss associated with diseases such as peri-implant loosening, periodontal disease and RA.

 

Dr Janet Coller, FTT Fricker Research Fellow

Dr Janet Coller has an established track record in Pharmacology and Pharmacogenomic medical research within the health areas of cancer, drug dependence, cardiology and solid-organ transplantation. Dr Coller was awarded an NHMRC CJ Martin Fellowship in 2000 to undertake Postdoctoral training in the world leading pharmacogenomics research group of Prof Michel Eichelbaum at the Dr Margarete-Fischer-Bosch Institute of Clinical Pharmacology. Here she conducted work to identify how genetic variability impacts on the therapeutic use of tamoxifen for breast cancer. In 2002 Dr Coller returned to the Discipline of Pharmacology, University of Adelaide to commence studies identifying important genetic variants that determine successful treatment of opioid dependence with methadone. More recently she has expanded her research to the emerging field of immunogenetics that has implications for therapeutics in the fields of cancer, epilepsy, organ transplantation, neurodegeneration and addiction. She has been recognized as an emerging investigator by her peers, receiving the New Investigator Awards of both major pharmacology / pharmaceuctical science societies in Australasia. More recently she received a 2007-08 Young Tall Poppy Science Award. She is the current co-chair of the ASCEPT Pharmacogenomics Special Interest Group that facilitates active collaboration between the leading pharmacogenomic researchers and raises the profile of pharmacogenomics in Australasia. Since 2000 she has obtained funds totaling $1.28 million from nationally competitive bodies and has also conducted specialized contract research for pharmaceutical companies. Dr Coller has international active research collaborations with colleagues in New Zealand, USA, and Germany in addition to extensive local collaborations. She consistently publishes in the top ranking clinical pharmacology and pharmacogenomics journals, and is a current editorial board member of the Open Drug Metabolism Journal. She has also filed 2 provisional patents related to her exciting new immunogenetics and addiction research with the potential of future commercial development.

Dr Renée Turner, NHMRC CJ Martin Post-Doctoral Research Fellow


Dr Renée Turner completed a BSc majoring in Pathology, Microbiology & Immunology at the University of Adelaide (2001). She continued her studies in Pathology, completing Honours (2002) on magnesium in traumatic brain injury. She was awarded an NHMRC Dora Lush Post-Graduate Research Fellowship and undertook a PhD (2007) examining the role of substance P in oedema formation following ischaemic stroke. This research led to a provisional patent relating to the treatment of reperfusion injury in ischaemic stroke. In 2006 she was selected as one of Australia’s top young scientists in the Fresh Science competition for communication of science in the media. 

In 2008 she was awarded an NHMRC CJ Martin Fellowship and moved to Sacramento California to undertake Post-Doctoral studies at the University of California, Davis. She worked with the leading research group of Frank Sharp, investigating gene expression profiles in clinical and experimental stroke, to guide treatment and diagnosis. She returned to Adelaide in 2010 to continue her research in the Discipline of Anatomy and Pathology. Her current work is focused on developing therapies for the treatment of cerebral oedema and raised intracranial pressure following stroke and traumatic brain injury, with a particular focus on the neuropeptide substance P and aquaporin water channels.

Dr Turner has active research collaborations with colleagues in USA and Germany, in addition to numerous local collaborations. She has numerous publications in peer-reviewed journals, review papers and book chapters, one patents, and is frequently asked to speak at national conferences and symposia.