Translational Mind and Brain Centre
Despite increasing investments into Neuroscience, Clinical Psychiatry, and related research, the prevalence rates of neuropsychiatric disorders and their associated burden of disease have been predicted to increase further.
On the other side, with the advancement of the Neurosciences and several biomedical technology platforms as well as through a broadening of interventions in Clinical Psychiatry, Psychiatry as a field has started to develop a better understanding of the causes and the potential for novel diagnostics and innovative treatments of severe mental illness. To further this development, the Translational Mind and Brain Centre focuses on research improving diagnostic processes and treatment outcomes and on research that enhances the Regeneration of Mind and Brain.
Research Strategy and Focus
The Translational Mind and Brain Centre at the University of Adelaide aims to fill the gap existing between clinical practice and advancement of Neuroscience research in Psychiatry. Our concept of Translational Mind and Brain builds on an integrated model between basic science, improved diagnostics and novel treatments of Psychiatric Disorders. We believe, that clinical practice informs the direction of Neuroscience research and vice versa, in that the Neurosciences improve diagnostics and treatments of Psychiatric Disorders. Research in this centre identifies clinical problems that are taken to the bench-site in a circular process feeding back into clinical practice. Vice versa, we focus on basic Neuroscience projects that have a clear translational application in clinical practice. A second main focus is laid on basic science research and clinical practice that enhances Regeneration of the Mind and Brain.
Strategy and Platforms
Key strategies and platforms include longitudinal clinical research cohorts, pharmacogenetics/-omics, developing integrated diagnostic processes and improving and predicting treatment responses, investigate cognitive, emotional and behavioural phenotypes across disorders, apply systems neuroscience, focus on enhancing neuroprotection and neuroregeneration in psychiatric disorders with a clinical focus on mood disorders (unipolar, bipolar disorder) and schizophrenia / psychosis.
This approach will advance a more rapid translation of neuroscience discoveries into clinical practice and vice versa and, importantly, it will improve the understanding, application and development of novel diagnostic procedures and treatments effective in severe mental illness.