You are here:

text zoom : S | M | L

Further Enquiries

Discipline of Paediatrics
The University of Adelaide
SA 5005
Australia
Email

Telephone: +61 8 8161 7266
Facsimile: +61 8 8161 7031

Molecular Immunology

LABORATORY HEAD :

A/Prof Simon Barry

Contact details

Research Staff

Tim Sadlon PhD
Jonathon Hutton PhD
Elizabeth Melville BSc (Hons)
Suzanne Bresatz BSc (Hons)
Angie Pollard
Sylvie Nobbs (Dip Med Lab Sci)
with Prof Heddy Zola, A/Prof Richard D'Andrea, Debbie Millard

Students

Patrick Quinn (PhD)
Nicola Leung (PhD)
Kai Mak (Hons)
Georgina Baldock (Hons)
Steve Pedderson (Hons)
Sophie White (yr 3)

GOALS

Simon Barry's lab is focused on function based gene discovery using viral vectors. We are developing tools for gene discovery, gene delivery and gene ablation, and applying them in immunological cell settings. The lab uses cellular and molecular approaches to identify and characterize genes involved in the function of a specialized subset of T cells that are CD4+ CD25+ double positive, and contain the regulatory T cell population. We are attempting to identify novel proteins on the surface of regulatory T cells, which may be useful as diagnostic or functional markers for autoimmune diseases. Vectors based on the third generation self inactivating lentiviruses are being developed for stable gene delivery and stable delivery of shRNAi for gene ablation. This is on a single gene basis as well as arrayed or complex mixture cDNA libraries.

Research Projects