Associate Professor David Torpy

Staff
Ms Jody Ngui - Clinical Trials Co-ordinator

Higher Degree students
Dr Hilal Al-Musalhi - MMedSci
Dr Jui Ho - PhD
Ms Elizabeth Mitchell - PhD
Ms Jennifer Keogh - PhD

Current Funded Research
2004 Royal Adelaide Hospital Clinical Research Grant - Relative adrenal insufficiency in septic shock. Definition and natural history; influence of plasma corticosteroid-binding globulin and its glycan isoforms. $15,000

2003-2004 Viertel Clinical Investigatorship $55,000  

Most recent publications
1. Joyner J, Hutley L, Torpy DJ, Bachmann AW, Prins J. Greater replication and differentiation of preadipocytes in inherited corticosteroid binding globulin deficiency. American Journal of Physiology - Endocrinology and Metabolism 2003;284:E1049-1054.

2. Mitchell E, Torpy DJ, Bagley CJ. Pregnancy-specific corticosteroid-binding globulin: high resolution separation of glycan isoforms. Hormone and Metabolic Research 2004;36:1-3.

3. Kleinig TJ, Torpy DJ. Milk-alkali syndrome: broadening the spectrum of causes to allow early detection. Internal Medicine Journal 2004;34:366-367.

4. Torpy DJ, Bachmann AW, Gartside M, Grice JE, Harris JM, Clifton P, Easteal S, Jackson RV, Whitworth JA. Association between chronic fatigue syndrome and the corticosteroid-binding globulin gene Ala Ser224 gene polymorphism. Endocrine Research 2004;30:417-429.

5. Bachmann AW, Sedgley TL, Jackson RV, Gibson JN, Young R.McD, Torpy DJ. Glucocorticoid receptor polymorphisms and post-traumatic stress disorder. Psychoneuroendocrinology 2005;30(3):297-306.

6. Jackson RV, Nye EJ, Grice JE, Hockings GI, Strakosch CR, Walters MM, Crosbie GV, Torpy DJ, Jackson RV. Early rise in blood pressure following adrenocorticotropin [1-24] administration in humans. Clinical and Experimental Pharmacology and Physiology 2001;28:773-775.

7. Nye EJ, Grice JE, Hockings GI, Strakosch CR, Crosbie GV, Walters MM, Torpy DJ, Jackson RV. The insulin hypoglycemia test: hypoglycemic criteria and reproducibility. Journal of Neuroendocrinology 2001;13(6):524-530.

8. Nye EJ, Grice JE, Hockings GI, Strakosch CR, Crosbie GV, Walters MM, Torpy DJ, Jackson RV. Adrenocorticotropin stimulation tests in patients with hypothalamic-pituitary disease: low-dose, standard high dose and 8-hour infusion tests. Clinical Endocrinology (Oxf) 2001;55:625-633.

9. Eaton HJ, Phillips PJ, Hanieh A, Cooper J, Bolt J, Torpy DJ. Rapid onset of pituitary apoplexy after goserelin implant for prostate cancer: Need for heightened awareness. Internal Medicine Journal 2001;31:313-314.

10. Torpy DJ, Bachmann AW, Grice JE, Fitzgerald SP, Phillips PJ, Whitworth JA, Jackson RV. Familial corticosteroid-binding globulin deficiency due to a novel null mutation: Association with fatigue and hypotension. Journal of Clinical Endocrinology and Metabolism 2001;86:3692-3700.

11. Torpy DJ, Mullen N, Chrousos GP, Nieman LK. Ectopic Cushing’s syndrome - Association with hypertension and hypokalemia: a series of 58 cases. Annals of the New York Academy of Sciences 2002;970:134-144.

Abstracts
1. Mitchell E, Torpy DJ, Bagley CJ. High resolution identification of pregnancy transcortin glycoforms. Proceedings of the Endocrine Society of Australia Annual Scientific Meeting, Melbourne, Sept. 2003, Abstract 346, Page 186.

2. Mitchell E, Bagley C, Clifton P, M. Noakes, Lewis J, Torpy D. Variability in corticosteroid-binding globulin levels with weight loss in humans. Proceedings of the Endocrine Society of Australia Annual Scientific Meeting, Melbourne, Sept. 2003, Abstract 195, Page 142.

3. McKenzie FD, Jackson RV, Finnimore AJ, Grice JE, Torpy DJ. The waking cortisol response in obstructive sleep apnoea. Proceedings of the Endocrine Society of Australia Annual Scientific Meeting, Melbourne, Sept. 2003, Abstract 196, pp 142-143.