Prof David Callen, PhD

Also check this link to the University Staff Directory as it may contain a more updated profile of this staff member including expertise and contact details.

Staff
Renee Schulz, Research Assistant
Margaret Yard, Technical Assistant

Higher Degree students
Mrs Zarqa Saif - PhD
Mr Paul Neilsen - PhD

Current Funded Research
2002-2006 NMHRC Program Grant: Understanding the Human Genome: Molecular mechanisms of Human Disease. Proportion to DFC, $389,400/year. 2004-2007 Susan G Komen Breast Cancer Foundation, USA: CBFA2T3 is a novel breast cancer tumour suppressor gene: investigation as a prognostic marker and development of drug targets. Total US$250,000.  

Most recent publications

1. Holm R, Knopp S, Kumar R, Lee J, Nesland J M, Tropè C, and Callen DF. (2007) Expression of ZNF652, a novel zinc finger protein, in vulvar carcinomas and its relation to prognosis. J Cin Path  Apr 27; [Epub ahead of print]
2. Kumar R, Manning J, Spendlove HE, Kremmidiotis G, McKirdy R, Lee J, Millband DN, Cheney KM, Stampfer MR, Dwivedi PP, Morris HA, Callen DF.  (2006) ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription. Mol Cancer Res  4(9):655-65.
3. Kumar R, Neilsen PM, Crawford J, McKirdy R, Lee J, Powell JA, Saif Z, Martin JM, Lombaerts M, Cornelisse CJ, Cleton-Jansen A-M, Callen DF. (2005) FBXO31 is the chromosome 16q24.3 senescence gene, a candidate breast tumor suppressor, and a component of an SCF complex. Cancer Res 65:11304-11313.
4. Martin J, Han C, Gordon LA, Terry A, Prabhakar S, She X, Xie G, Hellsten U, Chan YM, Altherr M, Couronne O, Aerts A, Bajorek E, Black S, Blumer H, Branscomb E, Brown NC, Bruno WJ, Buckingham JM, Callen DF, Campbell CS, et al (2004) The sequence and analysis of duplication-rich human chromosome 16. Nature 432:988-994.
5. Bais AJ, Gardner AE, McKenzie OL, Callen DF, Sutherland GR and Kremmidiotis G, (2004) Aberrant CBFA2T3B gene promoter methylation in breast tumors. Mol Cancer 3:22.
6. Speck P, Callen DF and Longnecker R, (2003) Absence of the Epstein-Barr virus genome in breast cancer-derived cell lines. J Natl Cancer Inst 95:1253-1254; author reply 1254-1255.